Antioxidant Vitamins are NOT the only source of Antioxidants

Other antioxidants are enzymes. These include glutathione peroxidase, superoxide dismutase and catalase. These are synthesized by the body. Supplementing these Antioxidants in synthetic form may not help you at all. Your physician can do blood tests to determine if your body is not producing enough of these enzymes. At that time they may recommend a supplement or they may just recommend you eat more foods that cause your body to produce more of these enzymes. You could have a liver imbalance or other disease which is either overworking these enzymes or not allowing your body to create enough of them. The advise here is see your physician before you run to the store and just start taking a handful of supplements.

A lot of damage is done by free radicals in mitochondria (damage to mitochondrial DNA, which is very much exposed to free radicals because of where its location between the inner and outer mitochondrial membranes; and the enzymes that copy it don’t do error-checking/correction, as the ones that copy the nuclear DNA do). Most antioxidants, however (including vitamin C and vitamin E) can’t get into mitochondria for various reasons (e.g. because it’s charged). But a group of scientists in Russia (led by V. Skulachev) has created a custom antioxidant (“Skulachev ion” is forming the point of the molecule and penetrates the mitochondrial membrane and the “antioxidising” part is attached behind it) that can enter the mitochondria and stays there preventing damage to DNA.

Posted by on Jul 8th, 2008 and filed under Antioxidants. You can follow any responses to this entry through the RSS 2.0. You can leave a response by filling following comment form or trackback to this entry from your site

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